The reigning champion, which led 2-1 from the first leg, was beaten 2-0 in Madrid and sent packing 3-2 on aggregate.
Antoine Griezmann scored twice to send Atletico through to the semifinals and end Barcelona's hopes of becoming the first team to retain the Champions League title.
Only once in the past eight seasons had Barcelona failed to reach the semifinal stage of the competition -- that was back in 2014 when it was knocked out in the last eight by Atletico.
Holders tumble
No team has ever successfully defended its Champions League title but this year was supposed to be different.
Only a few weeks ago Barcelona was playing football from another planet, it was steamrolling opponents with ease and scoring goals for fun.
There were few who believed Barcelona could be stopped as it embarked on a run of 39 consecutive games without defeat.
But the juggernaut has come to a shuddering halt -- and its main man appears to have gone missing.
Lionel Messi, the diminutive genius, has now failed to score for 452 minutes -- his longest drought since April 2010.
He might even exceed that dry spell if he fails to score within the opening 23 minutes of Sunday's clash with Valencia.
He might even exceed that dry spell if he fails to score within the opening 23 minutes of Sunday's clash with Valencia.
The forward, who has amassed an astonishing 499 career goals, failed to muster a single effort on target in the Champions League for the first time since April 2014 -- a game which was also against Atletico.
