Hamilton survived a scare at the start, when he ran wide at the first corner after locking a front tyre.
Hamilton is 19 points adrift with a total of 50 available in Brazil and Abu Dhabi.
The German will doubtless keep to his well-worn mantra that he is taking it one race at a time and trying to win each one, but he has the luxury of knowing he can afford to take it easy in both remaining races and clinch his first world title.