The World Health Organisation has declared the outbreak a public health emergency of international concern.
Motsoaledi says more than 34 countries, mostly in South and Central America, are already dealing with the virus.
He was briefing Parliament’s health committee earlier today.
Motsoaledi says while people who get infected usually experience mild symptoms and recover quickly, the virus has been linked to the birth of babies with abnormally small brains.
He says the biggest concern for South Africa is the risk posed to pregnant women traveling to affected countries.
“Our first advice is: do not travel. If you must, take all the precautions, make sure no mosquito comes near you or bites you because that is the only guarantee [that you will not be infected].”
