The illness is very different from cholera, which is caused by different bacteria, called Vibrio cholerae. Vibrio vulnificus infections do not spread directly from one person to another and are a serious health threat predominantly to persons with underlying illness, such as liver disease, or a compromised immune system.
Symptoms of infection with Vibrio vulnificus include:
- Acute illness, with a rapid decline in health following exposure
- If exposed by contamination of an open wound, increasing swelling, redness, and pain at the site of the wound
- Illness typically begins within 1-3 days of exposure, but begins as late as seven days after exposure for a small percentage of cases
- Fever
- Swelling and redness of skin on arms or legs, with blood-tinged blisters
- Low blood pressure and shock
Persons with immunocompromising conditions and especially those with chronic liver disease should avoid exposure of open wounds or broken skin to warm salt or brackish water, and avoid consuming undercooked shellfish harvested from such waters.
Otherwise healthy persons are at much lower risk of Vibrio vulnificus infection.
Vibrio vulnificus infection is diagnosed by microbiologic culture of wound, by blood cultures, or by stool culture in the case of patients who consumed raw or undercooked seafood and the infection is treated with antibiotics. Vibrio vulnificus wound infections should be treated with aggressive attention to the wound site.