Murray reeled off the final eight games as he dispatched French 13th seed Pouille 6-3, 6-0 to extend his winning streak to 17 matches.
"I thought I returned well today. I had chances in almost all of his service games throughout the match. And on this surface, obviously when it's a bit quicker, that's good," said Murray.
"I felt tired (this morning) because it was a late finish (from Wednesday night when Murray defeated Fernando Verdasco) but I felt all right once I got going," added the second seed, having equalled last season's career-best total of 71 wins.