In the most recent killing, 3-year-old Courtney Pieters was raped and murdered in Elsies River.
Her alleged killer appeared in the Goodwood magistrates court on Wednesday following his arrest on Sunday night, a day after Pieters' body was found in Epping.
Pieters is one of 19 children who've been killed in the Western Cape since January.
Mortimer Saunders appeared in court in connection with her murder, rape and kidnapping on Wednesday.
The National Prosecuting Authority's Eric Ntabazalila was at court: "From January up to today, there have been 19 children that have been killed in the Western Cape. Twelve of those cases will go to the high court."
